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Index > Protein center > BIRC5(Gene name) > Pig
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  • BIRC5 (Gene name),
  • Baculoviral IAP repeat-containing protein 5 (Protein name ),  BIRC5_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    BIRC5;
    Protein name:
    Baculoviral IAP repeat-containing protein 5;
    Alternative:
    Apoptosis inhibitor survivin;
    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    Monomer or homodimer. Exist as a homodimer in the apo state and as a monomer in the CPC-bound state (By similarity). When phosphorylated, interacts with HBXIP; the resulting complex binds pro-caspase-9, as well as active caspase-9, but much less efficiently. Component of the chromosomal passenger complex (CPC) composed of at least BIRC5/survivin, CDCA8/borealin, INCENP, AURKB and AURKC. Interacts with JTB. Interacts with CDCA8 and INCENP; interaction is direct. Interacts with EVI5. Interacts with GTP-bound RAN in both the S and M phases of the cell cycle. Interacts with USP9X. Interacts with tubulin.
    Function:
    Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. May play a role in neoplasia. May counteract a default induction of apoptosis in G2/M phase. Inhibitor of caspase-3 and caspase-7.
    Subcellular Location:
    Cytoplasm Nucleus Chromosome centromere Cytoplasm cytoskeleton spindle Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis. Colocalizes with AURKB at mitotic chromosomes.
    Protein Attributes:
    Sequence length:
    142
    Sequence:
    50:
    MSAPSLPPAW | QLYLKDHRIS | TFKNWPFLEG | CACTPERMAA | AGFIHCPTEN | 
    100:
    EPDLAQCFFC | FKELEGWEPD | DDPIEEHKKH | SSGCAFLSVK | KQFEELTLSE | 
    142:
    FLKLDKERAK | NKIAKETNNK | QKEFEETAKK | VRCAIEQLAA | SE
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Pig Baculoviral IAP repeat-containing protein 5
    Cat.:
    E2045h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Pig Baculoviral IAP repeat-containing protein 5
    Cat.:
    E2045m
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig Baculoviral IAP repeat-containing protein 5
    Cat.:
    E2045b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Pig Baculoviral IAP repeat-containing protein 5
    Cat.:
    E2045p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Pig Baculoviral IAP repeat-containing protein 5
    Cat.:
    E2045d
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Pig Baculoviral IAP repeat-containing protein 5
    Cat.:
    E2045r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Baculoviral IAP repeat-containing protein 5
    Cat.:
    U2045d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Baculoviral IAP repeat-containing protein 5
    Cat.:
    U2045b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Baculoviral IAP repeat-containing protein 5
    Cat.:
    U2045p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Baculoviral IAP repeat-containing protein 5
    Cat.:
    U2045r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Baculoviral IAP repeat-containing protein 5
    Cat.:
    U2045m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Pig Baculoviral IAP repeat-containing protein 5
    Cat.:
    U2045h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Pig Baculoviral IAP repeat-containing protein 5
    Cat.:
    P2045Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig Baculoviral IAP repeat-containing protein 5
    Cat.:
    P2045Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig Baculoviral IAP repeat-containing protein 5
    Polyclonal Antibody for Pig Baculoviral IAP repeat-containing protein 5
    Polyclonal Antibody for Pig Baculoviral IAP repeat-containing protein 5
    Polyclonal Antibody for Pig Baculoviral IAP repeat-containing protein 5
    Cat.:
    P2045Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Pig Baculoviral IAP repeat-containing protein 5
    Monoclonal Antibody for Pig Baculoviral IAP repeat-containing protein 5
    Monoclonal Antibody for Pig Baculoviral IAP repeat-containing protein 5
    Monoclonal Antibody for Pig Baculoviral IAP repeat-containing protein 5
    Monoclonal Antibody for Pig Baculoviral IAP repeat-containing protein 5
    Monoclonal Antibody for Pig Baculoviral IAP repeat-containing protein 5
    Protein for Pig Baculoviral IAP repeat-containing protein 5
    Protein for Pig Baculoviral IAP repeat-containing protein 5
    Protein for Pig Baculoviral IAP repeat-containing protein 5
    Protein for Pig Baculoviral IAP repeat-containing protein 5
    Protein for Pig Baculoviral IAP repeat-containing protein 5
    Protein for Pig Baculoviral IAP repeat-containing protein 5

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    References
    1. 1.
      "Isolation and mapping the pig homologs survivin (BIRC5) and effector cell protease receptor 1 (EPR1) genes."
      Cirera S. , Fredholm M.
      Cytogenet. Cell Genet.92:351-352(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Small intestine.
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